میکروبیولوژی

Substance

Common Sources

Chemical Composition

Activity

Lysozyme

Serum, saliva, sweat, tears

Protein

Bacterial cell lysis

Complement

Serum

Protein-carbohydrate lipoprotein complex

Cell death or lysis of bacteria; participates in inflammation

Basic proteins and polypeptides (histones, ß-lysins and other cationic proteins, tissue polypeptides)

Serum or organized tissues

Proteins or basic peptides

Disruption of bacterial plasma membrane

Lactoferrin and transferrin

Body secretions, serum, organized tissue spaces

Glycoprotein

Inhibit microbial growth by binding (withholding ) iron

Peroxidase

Saliva, tissues, cells (neutrophils)

Protein

Act with peroxide to cause lethal oxidations of cells

Fibronectin

Serum and mucosal surfaces

Glycoprotein

Clearance of bacteria (opsonization)

Interferons

Virus-infected cells, lymphocytes

Protein

Resistance to virus infections

Interleukins

Macrophages, lymphocytes

Protein

Cause fever; promote activation of immune system